Who's Line is it Anyways meets Fear Factor in “Let’s Play a Game”. Each week, a new crazed killer will put their cast of victims through their own twisted games. If the players succeed, they earn points. Losers take on disadvantages that may end up costing them future wins. Interspersed throughout are mini challenges where players can try to get rid of their hindrances as they fight for their lives. In the end, only one of them can earn the the spot of the night's sole survivor and escape the killer's evil clutches.